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Some of the nation’s most influential companies select the San Francisco Bay Area as their home base. Fifty-four percent of California’s Fortune 500 companies are headquartered here, including Chevron, Intel, Cisco Systems, Safeway, Google, Apple, Wells Fargo and Yahoo! The market is also particularly strong in its connection to biotechnology and is supported by an abundance of life science research and medical care institutions.

Sources: Fortune 500, 2010