American Gods is a big book in more ways than one; not only is it over six hundred pages long, but it deals with big ideas. The main character, Shadow, has been released from prison a few days early in order to be able to attend his wife's funeral. On the way home, he's recruited buy the mysterious Mr Wednesday.
It eventually transpires that Shadow has been recruited into a war between gods; the old gods, brought to America by the various immigrants over time, and the new gods of television and media and so forth.
The nice thing about this book is the amount of mythology hidden to a lesser or greater extent in the storytelling. Some of the gods are more easily recognisable than others; the jump from "Mr Nancy" to "Anansi", for instance, is not so great, whereas the link between Mr Wednesday to Odin is not as immediately obvious. But you don't have to have much grounding in mythology to be able to enjoy the book, which is one of the great things about it; there are plenty of layers to be unpicked, if you're that way inclined, but on the other hand, you can just sit back and enjoy Neil Gaiman's masterful storytelling.
The added benefit of this particular edition is the author interview in the back, which gives that extra little insight into the book. It's apparently also the author's preferred text, though having read both versions, I have to say that for the reader it makes little difference.