1984-1990  |
Basophil degranulation
1) Basophil degranulation by high dilutions of anti-IgE antibodies.
2) Inhibition of basophil degranulation by high dilutions of histamine.
*(in fact achromasia, i.e. loss of staining by alkaline dyes, without histamine release) |
|
| 1990-1998 |
Guinea-pig heart
Isolated perfused guinea-pig heart (Langendorff). We have tested more than 30 substances, first at high dilution, then by direct transmission using an amplifier and finally by recording/reply of the molecular signal by means of a computer. |
|
|
Neutrophil activation
Neutrophil activation by Phorbol-Myristate-Acetate transmitted by the amplifier
in real time. (See
article in "Medical Hypotheses" in the bibliography list) |
|
| 1997-1998 |
Ag/Ab precipitation
Detection of the recorded "signal" of bacteria (and, by extension, of any antigen or antibody) by playing it to an immune reaction specific to this signal. |
|
| 1998 |
Skin test
Intradermal injection to guinea-pigs or rabbits of water "informed" with the signal of vasodilators such as histamine, serotonin, acetylcholine, bradykinin induces local skin vasodilation inhibited by the specific inhibitor of the original molecule. |
|
| 1999-2001 |
Plasma coagulation
Water "informed" with the recorded signal of heparin delays or inhibits plasma coagulation. (See graph attached to our recent newsletter).
We have setup an automatic bioanalyser which performs the whole method without
human intervention. (See
the video) |
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